Zhang Laboratory

Facilitating personalized diagnosis and treatment of childhood diseases
Pathological Jaundice

Pathological Jaundice

Jaundice is caused by too much bilirubin, a breakdown product of red blood cells. After being processed in the liver, bilirubin is passed out of body in poo. Newborn babies have a high number of red blood cells that are broken down and replaced frequently. Their livers are less effective...
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Facilitating personalized diagnosis and treatment of childhood diseases

We study how immune cells go awry in pediatric inflammatory, allergic, autoimmune and autoinflammatory conditions.

We strive to identify key pathogenic mechanisms and develop novel diagnostic and treatment methods that may improve the quality of life in children.

Cutting-edge technologies, including disease-causal and risk gene identification, single-cell based disease tissue profiling, and mechanistic exploration using bioinformatic, biochemical, immunological and animal model studies, have shaped our approach in helping the clinicians to achieve personalized diagnosis and pathogenesis-based treatment practice.